Pantoprazole with Domperidone is used to reduce the amount of acid produced by the stomach, to treat or prevent conditions such as heartburn, Gastritis, ulcers and GERD. For best results, it should be taken just before a meal. It can help with the greater amount of stomach acid that is always produced. The capsules are generally offered in the composition of Pantoprazole 40mg & Domperidone 30 mg sustained release.
Pantoprazole: Pantoprazole is unstable in acid and is administered orally in the form of an enteric-coated tablet. Absorption takes place in the small intestine. On average, the maximum serum/plasma concentrations are approximately 2 to 3 micrograms/ml about 2 ½ hrs after administration of 40 mg pantoprazole daily.
Domperidone: In man, peak plasma level of domperidone occurs within 30 minutes after oral (fasted) administration. Peak plasma concentrations are 20 ng/ml after a single 10mg tablet, and 70 to 100 ng/ml after oral doses of 60 mg. After oral administration of 40 g 4-domperidone to healthy volunteers, 31st, of the radioactivity is excreted in the urine and 66 % in the faeces over a period of 4 days.
Latest prescription information about Pantoprazole and Domperidone. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy.
Warnings and Precautions :
• Pantoprazole is not recommended for children less than 12years.
• Caution should be exercised in patients with history of liver disease, any other gastrointestinal disorders, any allergy and during pregnancy.
• Avoid prolonged usage of this medication.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.